Yanan Du
Yanan Du, PhD,
Associate Professor (Tenured)
Department of Biomedical Engineering, School of Medicine
Tsinghua University
Medical Science Building, Beijing, 100084
Email:duyanan@tsinghua.edu.cn
Labweb: http://dulab.med.tsinghua.edu.cn/

Biography:

Dr. Yanan Du received his B.Eng. degree in Chemical Engineering from Tsinghua University and Ph.D. in Bioengineering from National University of Singapore. Dr. Du completed his postdoctoral training at Harvard-MIT Division of Health Science and Technology, MIT and Brigham &Women's hospital, Harvard Medical School. In 2010, he joined the faculty at Department of Biomedical Engineering, School of Medicine, Tsinghua University as principal investigator and obtained tenure in 2016. Dr. Du's research focuses on developing Micro-engineered Cell-based Assays and Therapy Platform for drug screening, disease study and regenerative therapy.


Abstract:

Engineering 3D hepatic microenvironment for drug Evaluation with improved predictability

We have developed 3D microtissue array containing repeated micro-engineered biomimetic microenvironments by integration of biomaterials and microfabrication technology.  Microtissues in varied pathological and physiological states have been constructed by fine-tuning the microenvironments for physio/pathological investigation and drug screening. Here I will present such efforts in engineering 3D hepatic microenvironments to build normal or tumor liver microtissue arrays for high throughput screening and evaluation of drug efficacy and toxicity. The microtissue array platform is expected to upgrade the existing 2D cell culture based high throughput drug screening to a 3D organotypic level with increased predictability and accuracy.
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Key Dates

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Deadline for early registration
  September 15, 2017