Yu-Chen (Andy) Hu
Yu-Chen (Andy) Hu, Ph.D.
Program Chair, TERMIS-AP 2016 meeting
Fellow, American Institute for Medical and Biological Engineering (AIMBE)
Distinguished Professor and Chairman
Department of Chemical Engineering, National Tsing Hua University
Hsinchu, Taiwan.
E-mail: yuchen@che.nthu.edu.tw

Biography:

Dr. Yu-Chen Hu received his BS degree in Chemical Engineering from National Taiwan University (1992) and earned his PhD degree in Chemical Engineering from University of Maryland (USA) in 1999.  He worked as a post-doc at the National Institutes of Health from 1999 to 2000 and returned to the Department of Chemical Engineering, National Tsing Hua University, Taiwan, in 2000. Dr. Hu' s main research interests include vaccine development, gene therapy, tissue engineering, cancer therapy and synthetic biology.  Dr. Hu's lab has developed the enterovirus 71 (EV71) vaccine based on virus-like particle technology and avian influenza vaccine based on baculovirus vector.  Dr. Hu also utilizes baculovirus as a gene vector to deliver various genes encoding growth factor or microRNA into adult stem cells/cell sheet for the modulation of cellular differentiation states and tissue regeneration.  His recent animal studies have demonstrated that the baculovirus-engineered cells, after implantation into animals, repair massive defects in cartilage and bone. Dr. Hu’s lab also exploits baculovirus-engineered stem cell sheet for the management of myocardial infarction and bone infection. Dr. Hu' s works have paved a new avenue to the use of baculovirus as a novel vector for regenerative medicine. Dr. Hu has won the Asia Research Award (Society of Chemical Engineers, Japan), Outstanding Research Award (Ministry of Science and Technology, 2006, 2014), BEST Biochemical Engineering Achievement Award,  Wu Ta-You Memorial Award (NSC), Outstanding Academia-Industry Research Award and Outstanding Young Investigator Award in Taiwan.  He is inducted as a fellow of American Institute for Medical and Biological Engineering (AIMBE), and is elected the Member of the Tissue Engineering International & Regenerative Medicine Society-Asia Pacific (TERMIS-AP) Council and the Vice President of Biotechnology and Biochemical Engineering Society of Taiwan.  He is the Program Chair of the TERMIS-AP meeting, 2016. He also sits on the editorial board of 10 international journals and currently serves as the associated editor of Current Gene Therapy and deputy editor of Journal of Taiwan Institute of Chemical Engineers.


Abstract: 

RNA Therapeutics and Anabolic Gene Delivery for Tissue Regeneration

Regenerative medicine requires coordinated functions of cells, materials and appropriate signaling. Recent years have witnessed the marriage of regenerative medicine and gene delivery by which various genes encoding anabolic/catabolic proteins or RNA therapeutics are delivered into cells to potentiate the tissue regeneration. This presentation will focus on the use of viral vectors for genetic modification of mesenchymal stem cells derived from bone marrow or adipose tissue for tissue regeneration. In particular, emphasis is placed on the applications of baculovirus, an emerging nonpathogenic gene delivery vector, for the delivery of various anabolic genes and miRNA mimics/sponges to repair tissues.
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  Abstract continue accepting
  
Deadline for early registration
  September 15, 2017