Yong Huang
Yong Huang, Ph.D.
University of Florida,
Gainesville, FL
Email: yongh@ufl.edu

Biography:

Dr. Yong Huang is a professor of Mechanical and Aerospace Engineering, Biomedical Engineering, and Materials Science and Engineering at the University of Florida, Gainesville, Florida. His research interests are two-fold: 1) processing of biological and engineering materials for healthcare/energy applications; and 2) understanding of material dynamic behaviors during manufacturing and process-induced damage or defect structures. His current research topics include three-dimensional (3D) printing of biological and engineering structures, precision engineering of medical implants and performance evaluation of machined implants, and fabrication of polymeric microspheres / microcapsules / hollow fiber membranes. He served as the Technical Program Chair for the 2010 American Society of Mechanical Engineers International Manufacturing Science and Engineering Conference (ASME MSEC 2010) and the 2012 International Symposium on Flexible Automation (ISFA 2012). He received various awards for his manufacturing research contributions including
the ASME Blackall Machine Tool and Gage Award (2005), the Society of Manufacturing Engineers Outstanding Young Manufacturing Engineer Award (2006), the NSF CAREER Award (2008), and the ASME International Symposium on Flexible Automation Young Investigator Award (2008). He received his Ph.D. in Mechanical Engineering from the Georgia Institute of Technology in 2002 and is a Fellow of ASME.


Abstract:

Bioprinting: Implementation, Process Dynamics, and Process‐Induced Cell Injury

Maskless (including extrusion-, laser-, and inkjet-based) three-dimensional (3D) cell bioprinting is a revolutionary advance for printing arbitrary cell patterns as well as creating heterogeneous
living constructs. Unfortunately, process-induced thermomechanical injury to cells as well as other biomaterials during printing still poses a significant challenge to ensuring satisfactory post-transfer cell viability. Using a representative laser bioprinting technology (laser-induced forward transfer) as a jet-based model system, we have been addressing the aforementioned
printing-induced cell injury challenge by studying the process-induced cell thermomechanical loading during the cell droplet formation and landing processes and the post-transfer cell viability based on the process-induced thermomechanical loading. In this talk, the perspective of ongoing bioprinting research and various bioprinting technologies are first introduced. Then the modeling of the laser-induced cellular droplet formation and landing processes is discussed. The relationship between the mechanical loading information and the post-transfer cell injury/viability is further established through an apoptosis signaling pathway-based modeling approach. Finally, this talk shares some thoughts regarding basic scientific challenges related to bioprinting.
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Deadline for early registration
  September 15, 2017